Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.77 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971264 | 0.77 | CCR3 (0.53) | CCR3ACHE | |
| SCHEMBL9599982 | 0.75 | CCR3 (0.55) | CCR3ACHE | |
| SCHEMBL9599973 | 0.74 | CCR3 (0.54) | CCR3ACHE | |
| SCHEMBL8971088 | 0.73 | CCR3 (0.57) | CCR3ACHE | |
| SCHEMBL8971084 | 0.73 | CCR3 (0.57) | CCR3ACHE | |
| SCHEMBL8971012 | 0.73 | ADRA1D (0.61) | CCR3ACHE | |
| SCHEMBL8971112 | 0.71 | L3MBTL1 (0.55) | CCR3ACHE | |
| SCHEMBL29381887 | 0.71 | CCR3 (0.75) | CCR3ACHECARM1PRMT6 | |
| SCHEMBL9427625 | 0.70 | CCR3 (0.56) | CCR3ACHE | |
| SCHEMBL9427623 | 0.70 | CCR3 (0.56) | CCR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480892-A | SIGMA RECEPTOR ANTAGONISTS; TREATMENT OF PHYSIOLOGICAL OR DRUG INDUCED PSYCHOSIS AND DYSKINESIA | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5356906-A | (N-phthalimidoalkyl) piperidines useful as treatments for psychosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-18 | — | — | US | disclosed |