⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595791 | 0.80 | — | — | |
| SCHEMBL2161323 | 0.77 | CRHBP (0.32) | — | |
| SCHEMBL1832834 | 0.77 | — | — | |
| SCHEMBL24050940 | 0.75 | — | — | |
| SCHEMBL5517591 | 0.75 | — | — | |
| SCHEMBL5517584 | 0.73 | — | — | |
| SCHEMBL7754376 | 0.70 | — | — | |
| SCHEMBL10935045 | 0.68 | SCN2A (0.40) | — | |
| Phosphonic Acid SCHEMBL8386186 | 0.67 | — | — | |
| SCHEMBL1528219 | 0.65 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605393-A1 | TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2025-08-27 | — | — | EP | claimed |
| US-20240228503-A1 | TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-07-11 | — | — | US | claimed |
| WO-2024083773-A1 | TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-04-25 | — | — | WO | claimed |
| CN-117285985-A | Low-dynamic surface tension insulating layer buffer cleaning liquid and preparation method and application thereof | 四川格林达电子材料有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-116425761-A | Trifluoromethyl 1,2, 4-triazole compound containing spiro oxindole skeleton and preparation method thereof | 河北医科大学 | 2023-07-14 | — | — | CN | claimed |
| CN-113402522-B | Fluorine-containing [1,2,4] triazole [4,3-b ] [1,2,4,5] tetrazine ammonium nitrate and preparation method thereof | 四川轻化工大学 | 2023-01-24 | — | — | CN | claimed |
| CN-114409605-A | Trifluoromethyl-containing 1,2, 4-triazole derivative and preparation method and application thereof | 上海交通大学医学院附属瑞金医院 | 2022-04-29 | — | — | CN | claimed |
| CN-110194749-B | Method for synthesizing 3-trifluoro (difluoro) methyl-1, 2, 4-triazole-5-ketone compound | 福州大学 | 2022-04-26 | — | — | CN | claimed |
| CN-109761988-A | The preparation method for treating the drug sitagliptin of diabetes | 深圳市第二人民医院 | 2019-05-17 | — | — | CN | claimed |
| CN-101973997-B | Method for preparing sitagliptin phosphate side chain | UNIV ZHEJIANG | 2012-06-06 | — | — | CN | claimed |
| JP-H08509236-A | — | — | 1996-10-01 | — | — | JP | claimed |
| JP-H08509237-A | — | — | 1996-10-01 | — | — | JP | claimed |
| EP-0698014-A1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-02-28 | — | — | EP | claimed |
| EP-0695297-A1 | 1,5-BENZODIAZEPINES USEFUL AS GASTRIN OR CCK-ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-02-07 | — | — | EP | claimed |
| WO-1994025445-A1 | 1,5-BENZODIAZEPINES USEFUL AS GASTRIN OR CCK-ANTAGONISTS | GLAXO S.P.A. (IT) | 1994-11-10 | — | — | WO | claimed |
| WO-1994025444-A1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO SPA (IT) | 1994-11-10 | — | — | WO | claimed |
| CN-1074216-A | Urea derivative | GLAXO GROUP LTD (GB) | 1993-07-14 | — | — | CN | claimed |
| WO-1993008175-A1 | BENZODIAZEPINE DERIVATIVES AS ANTAGONISTS OF GASTRIN AND/OR CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1993-04-29 | — | — | WO | claimed |
| EP-0538945-A1 | Benzodiazepine derivatives, and their use as antagonists of gastrin and/or cholecystokinin | GLAXO GROUP LIMITED (GB) | 1993-04-28 | — | — | EP | claimed |
| US-4038405-A | MITICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1977-07-26 | — | — | US | claimed |