Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601371 | 0.95 | DRD2 (0.68) | DRD2HTR1ADRD4 | |
| SCHEMBL9587786 | 0.84 | DRD2 (0.70) | DRD2HTR1ADRD4 | |
| SCHEMBL10781927 | 0.84 | DRD2 (0.70) | DRD2HTR1ADRD4 | |
| SCHEMBL9588981 | 0.83 | DRD2 (0.73) | DRD2HTR1ADRD4 | |
| SCHEMBL10836726 | 0.83 | DRD2 (0.73) | DRD2HTR1ADRD4 | |
| SCHEMBL9527403 | 0.83 | DRD2 (0.84) | DRD2HTR1ADRD4 | |
| SCHEMBL11004867 | 0.83 | DRD2 (0.72) | DRD2HTR1ADRD4 | |
| SCHEMBL9601267 | 0.83 | DRD2 (0.65) | DRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL10782020 | 0.82 | DRD2 (0.70) | DRD2HTR1ADRD4 | |
| SCHEMBL10787025 | 0.82 | DRD2 (0.68) | DRD2HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309544-B1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-10 | — | — | EP | claimed |
| US-4748240-A | Psychotropic bicyclic imides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-05-31 | — | — | US | claimed |
| EP-0309544-B1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-10 | — | — | EP | disclosed |
| US-4748240-A | Psychotropic bicyclic imides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |