Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL511620 | 0.88 | — | — | |
| SCHEMBL292569 | 0.87 | GNAO1 (0.34) | S1PR1S1PR3GNAO1SIGMAR1CXCR4 | |
| SCHEMBL294978 | 0.86 | GNAO1 (0.36) | S1PR1S1PR3GNAO1SIGMAR1CXCR4 | |
| SCHEMBL294844 | 0.82 | CXCR4 (0.33) | GNAO1CXCR4GNAI3GNAI1 | |
| SCHEMBL19677010 | 0.79 | CXCR4 (0.36) | GNAO1CXCR4GNAI3GNAI1 | |
| SCHEMBL294119 | 0.77 | GNAO1 (0.41) | GNAO1SIGMAR1GNAI3GNAI1 | |
| SCHEMBL15095870 | 0.76 | GNAO1 (0.41) | S1PR1S1PR3GNAO1SIGMAR1GNAI3 | |
| SCHEMBL294449 | 0.75 | CXCR4 (0.33) | GNAO1CXCR4GNAI3GNAI1 | |
| SCHEMBL2702582 | 0.75 | GNAO1 (0.43) | GNAO1SIGMAR1GNAI3GNAI1 | |
| SCHEMBL292193 | 0.75 | LTA4H (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |