Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974031 | 0.87 | ALDH1A1 (0.75) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL10969206 | 0.83 | ALDH1A1 (0.69) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL10970753 | 0.83 | ALDH1A1 (0.69) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL10975385 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL18272456 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL10969480 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL10970972 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL9600395 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL11118817 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL8315703 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TP53LMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |