SCHEMBL9600938

SCHEMBL9600938

CC(=O)Nc1c(I)c(C=O)c(I)c(N(C)C(C)=O)c1I

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816387 0.82 LMNA (0.53) LMNASMN1; SMN2
SCHEMBL20471520 0.82 LMNA (0.48) LMNASMN1; SMN2
SCHEMBL9255096 0.78 LMNA (0.40) LMNA
Metrizoic Acid SCHEMBL37641 0.77 LMNA (0.52) LMNASMN1; SMN2
Metrizoic Acid SCHEMBL29570734 0.77 LMNA (0.52) LMNASMN1; SMN2
Metrizoic Acid SCHEMBL1236887 0.76 LMNA (0.51) LMNASMN1; SMN2
SCHEMBL8492195 0.76 LMNA (0.53) LMNASMN1; SMN2
Metrizoic Acid SCHEMBL1237887 0.76 LMNA (0.51) LMNASMN1; SMN2
SCHEMBL9600933 0.76 LMNA (0.42) LMNA
Metrizoic Acid SCHEMBL8060104 0.75 LMNA (0.64) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547126-A1 POLYMERS CONTAINING DIESTER UNITS. NYCOMED IMAGING AS (NO) 1993-06-23 EP disclosed
WO-1992004392-A1 POLYMERS CONTAINING DIESTER UNITS HOLMES, MICHAEL, JOHN (GB) 1992-03-19 WO disclosed