Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16342153 | 0.83 | LMNA (0.49) | LMNA | |
| SCHEMBL9600938 | 0.78 | LMNA (0.42) | LMNA | |
| Metrizoic Acid SCHEMBL37641 | 0.74 | LMNA (0.52) | LMNA | |
| Metrizoic Acid SCHEMBL29570734 | 0.74 | LMNA (0.52) | LMNA | |
| SCHEMBL9600933 | 0.72 | LMNA (0.42) | LMNA | |
| Metrizoic Acid SCHEMBL1237887 | 0.72 | LMNA (0.51) | LMNA | |
| SCHEMBL8492195 | 0.72 | LMNA (0.53) | LMNA | |
| Metrizoic Acid SCHEMBL1236887 | 0.72 | LMNA (0.51) | LMNA | |
| SCHEMBL9423182 | 0.72 | LMNA (0.50) | LMNA | |
| Metrizoic Acid SCHEMBL8060104 | 0.71 | LMNA (0.64) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9387267-B2 | Iodine-containing radial-shaped macromolecular compounds, preparation method thereof and contrast media compositions for CT comprising the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-07-12 | — | — | US | disclosed |
| US-20130150529-A1 | IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2013-06-13 | — | — | US | disclosed |
| US-5416223-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1995-05-16 | — | — | US | disclosed |
| US-5370861-A | Iodinated esters contrast medium and use | NYCOMED IMAGING AS (NO) | 1994-12-06 | — | — | US | disclosed |
| EP-0452377-B1 | IODINATED ESTERS | NYCOMED IMAGING AS (NO) | 1994-09-21 | — | — | EP | disclosed |
| EP-0452377-A1 | IODINATED ESTERS. | HOLMES MICHAEL JOHN (GB) | 1991-10-23 | — | — | EP | disclosed |
| WO-1990007491-A1 | IODINATED ESTERS | NYCOMED AS (NO) | 1990-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150529-A1 | IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME | IGFBP1, IGFBP5, IGFBP2 | LMNA 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.