Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603785 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRGLACHRNB2CHRNB4 | |
| SCHEMBL3483620 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRELANEGLATACR3 | |
| SCHEMBL28207526 | 0.83 | CHRM2 (0.52) | ALDH1A1TSHRGLACHRNB2CHRNB4 | |
| SCHEMBL1203729 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1TSHRGLAMAPTSMN1; SMN2 | |
| SCHEMBL10777121 | 0.81 | TSHR (0.45) | ALDH1A1TSHRGLASMN1; SMN2 | |
| SCHEMBL18190856 | 0.80 | MAPT (0.43) | ALDH1A1TSHRELANEGLATACR3 | |
| SCHEMBL2707534 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRGLAMAPTSMN1; SMN2 | |
| SCHEMBL5188456 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRELANEGLATACR3 | |
| SCHEMBL84134 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GLAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6717574 | 0.77 | TSHR (0.49) | ALDH1A1TSHRGLAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |