Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437473 | 0.86 | CYP1A2 (0.39) | THRBTHRAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL28121766 | 0.83 | L3MBTL1 (0.46) | THRBTHRAL3MBTL1GLAKDM4E | |
| SCHEMBL9854379 | 0.82 | KMT2A (0.35) | THRBTHRAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL28297685 | 0.81 | THRB (0.52) | THRBTHRAL3MBTL1GLAKDM4E | |
| SCHEMBL6271214 | 0.81 | L3MBTL1 (0.35) | L3MBTL1GLAKDM4EKMT2AALDH1A1 | |
| SCHEMBL3765449 | 0.80 | HCAR2 (0.42) | THRBTHRAKMT2AALDH1A1MAPT | |
| SCHEMBL19458696 | 0.80 | THRB (0.38) | THRBTHRAKMT2AALDH1A1HCAR2 | |
| SCHEMBL181491 | 0.80 | HPGD (0.43) | THRBTHRAL3MBTL1KDM4EKMT2A | |
| SCHEMBL11107994 | 0.80 | THRB (0.38) | THRBTHRAKMT2AALDH1A1HCAR2 | |
| SCHEMBL28563446 | 0.80 | KDM4E (0.40) | THRBKDM4EKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305545-B1 | SUBSTITUTED ACRIDINE DERIVATIVES AND THEIR USE | Hitachi Chemical Co., Ltd. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5089377-A | Acridin-9-yl acrylates | ASAHI DENKA KOGYO K.K. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-5045433-A | Photopolymerization initiators | HITACHI CHEMICAL CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| US-4985564-A | Acridine compound and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0360443-A1 | Acridine compound and photopolymerizable composition using the same | Hitachi Chemical Co., Ltd. (JP) | 1990-03-28 | — | — | EP | disclosed |