Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208882 | 1.00 | MEN1 (0.51) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL5605989 | 0.93 | MEN1 (0.53) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL6460660 | 0.93 | MEN1 (0.53) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL676076 | 0.89 | CYP2C19 (0.49) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL29484650 | 0.89 | CYP2C19 (0.49) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL676077 | 0.89 | CYP2C19 (0.49) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9209412 | 0.86 | NAMPT (0.38) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9208869 | 0.81 | KMT2A (0.58) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9600959 | 0.79 | CYP2C9 (0.38) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9211867 | 0.79 | CYP2C9 (0.38) | MEN1KMT2ACYP2C9ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |