Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601289 | 0.68 | TAAR1 (0.35) | TAAR1TSHRL3MBTL1ADRA1DHSD17B10 | |
| SCHEMBL5944840 | 0.63 | TAAR1 (0.36) | TAAR1TSHRL3MBTL1HSD17B10ADRA2A | |
| SCHEMBL31617182 | 0.62 | TAAR1 (0.35) | TAAR1TSHRL3MBTL1ADRA1DHSD17B10 | |
| SCHEMBL121154 | 0.61 | — | — | |
| Ammonia Solution, Strong SCHEMBL30464657 | 0.59 | — | — | |
| Iodide SCHEMBL28629698 | 0.59 | — | — | |
| Bromide SCHEMBL28986398 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL3194041 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL11377269 | 0.59 | — | — | |
| SCHEMBL4457103 | 0.59 | TAAR1 (0.42) | TAAR1TSHRL3MBTL1ADRA1DHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206415-B1 | (4-PIPERIDINYLMETHYL AND -HETERO)PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-27 | — | — | EP | disclosed |