SCHEMBL960130

SCHEMBL960130

COC(=O)CCC[SiH](OC)OC

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
LMNA P02545 4/20 0.44
ALDH1A1 P00352 2/20 0.44
KMT2A Q03164 4/20 0.43
MEN1 O00255 2/20 0.43
CA12 O43570 1/20 0.39
CA14 Q9ULX7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
RECQL P46063 1/20 0.39
EPHX2 P34913 1/20 0.39
GLA P06280 1/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28109806 0.86 TSHR (0.57) TSHRLMNAALDH1A1KMT2AMEN1
SCHEMBL524100 0.77 TSHR (0.61) TSHRLMNAALDH1A1KMT2AMEN1
SCHEMBL28238018 0.77 TSHR (1.00) TSHRLMNAALDH1A1KMT2AMEN1
SCHEMBL27953228 0.77 TSHR (0.88) TSHRLMNAALDH1A1KMT2AMEN1
SCHEMBL50039 0.77 TSHR (1.00) TSHRLMNAALDH1A1KMT2AMEN1
SCHEMBL14975 0.77 TSHR (0.88) TSHRLMNAALDH1A1KMT2AMEN1
SCHEMBL8076331 0.75 TSHR (0.82) TSHRLMNAALDH1A1KMT2AMEN1
SCHEMBL3503548 0.75 TSHR (0.82) TSHRLMNAALDH1A1KMT2AMEN1
Dimethyl Succinate SCHEMBL8829301 0.75 TSHR (0.82) TSHRLMNAALDH1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL21436145 0.75 TSHR (0.82) TSHRLMNAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2026-02-17 US disclosed
CN-111607089-B Functional polyhydrosilsesquioxane resin compositions, methods of producing the same, and uses thereof 彼博股份有限公司 2023-10-10 CN disclosed
US-20220162391-A1 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2022-05-26 US disclosed
EP-3931639-A1 FUNCTIONAL HYDROGEN SILSESQUIOXANE RESINS AND THE USE THEREOF Pibond Oy (FI) 2022-01-05 EP disclosed
CN-111607089-A Functional polyhydrosilsesquioxane resin compositions, methods of producing the same, and uses thereof 彼博股份有限公司 2020-09-01 CN disclosed
CN-107209303-B Far infrared ray reflective film, dispersion for forming far infrared ray reflective film, method for producing far infrared ray reflective film, far infrared ray reflective glass, and window 富士胶片株式会社 2020-07-14 CN disclosed
US-20110000658-A1 HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2011-01-06 US disclosed
EP-2239137-A1 HYDROPHILIC MEMBERS FUJIFILM Corporation (JP) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof MACF1, RTF1, ERCC4 TSHR 3190/4885LMNA 948/4885ALDH1A1 2112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.