⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963903 | 0.78 | HRH3 (0.73) | — | |
| SCHEMBL5513184 | 0.77 | — | — | |
| SCHEMBL128969 | 0.74 | — | — | |
| SCHEMBL1268284 | 0.74 | — | — | |
| SCHEMBL15223334 | 0.74 | — | — | |
| SCHEMBL8964986 | 0.74 | HRH3 (0.79) | — | |
| SCHEMBL8963886 | 0.74 | HRH3 (0.75) | — | |
| SCHEMBL8963957 | 0.72 | HRH3 (0.80) | — | |
| Hydrochloric Acid SCHEMBL7090498 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL4554002 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159546-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-9931415-B2 | Pyrrolobenzodiazepine-antibody conjugates | MEDIMMUNE LIMITED (GB) | 2018-04-03 | — | — | US | disclosed |
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| WO-1979000466-A1 | ALKYLATION METHOD OF 4(5)-MERCAPTOMETHYL-IMIDAZOL WITH AZIRIDIN DERIVATES | CRC RICERCA CHIM (CH) | 1979-07-26 | — | — | WO | disclosed |