Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.58 |
| ▸ | FAAH | O00519 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601551 | 1.00 | TAAR1 (0.61) | TAAR1TBXAS1FAAH | |
| SCHEMBL9601217 | 0.99 | TAAR1 (0.60) | TAAR1TBXAS1FAAH | |
| SCHEMBL9601207 | 0.99 | TAAR1 (0.60) | TAAR1TBXAS1FAAH | |
| SCHEMBL9602359 | 0.92 | TAAR1 (0.64) | TAAR1TBXAS1FAAH | |
| SCHEMBL9602373 | 0.92 | TAAR1 (0.64) | TAAR1TBXAS1FAAH | |
| SCHEMBL8305934 | 0.80 | TAAR1 (0.67) | TAAR1FAAH | |
| SCHEMBL8305938 | 0.80 | TAAR1 (0.67) | TAAR1FAAH | |
| SCHEMBL2635980 | 0.80 | TBXAS1 (0.59) | TBXAS1 | |
| SCHEMBL2635981 | 0.80 | TBXAS1 (0.59) | TBXAS1 | |
| SCHEMBL12186568 | 0.80 | TBXAS1 (0.59) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221601-B1 | [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-10 | — | — | EP | disclosed |
| US-5180832-A | Chemical intermediate for thromboxane A2 inhibitor | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-19 | — | — | US | disclosed |
| US-4963573-A | INHIBIT BIOSYNTHESIS OF THROMBOXANE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-10-16 | — | — | US | disclosed |
| US-4746671-A | THROMBOXANE SYNTHETASE INHIBITION | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-05-24 | — | — | US | disclosed |
| EP-0221601-A1 | [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-05-13 | — | — | EP | disclosed |