Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 11/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602373 | 1.00 | TAAR1 (0.64) | TAAR1TBXAS1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9601562 | 0.92 | TAAR1 (0.61) | TAAR1TBXAS1FAAH | |
| SCHEMBL9601551 | 0.92 | TAAR1 (0.61) | TAAR1TBXAS1FAAH | |
| SCHEMBL9601217 | 0.91 | TAAR1 (0.60) | TAAR1TBXAS1FAAH | |
| SCHEMBL9601207 | 0.91 | TAAR1 (0.60) | TAAR1TBXAS1FAAH | |
| SCHEMBL8305934 | 0.82 | TAAR1 (0.67) | TAAR1SMN1; SMN2ALDH1A1FAAHKDM4E | |
| SCHEMBL8305938 | 0.82 | TAAR1 (0.67) | TAAR1SMN1; SMN2ALDH1A1FAAHKDM4E | |
| SCHEMBL2635932 | 0.75 | TBXAS1 (0.58) | TBXAS1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2635935 | 0.75 | TBXAS1 (0.58) | TBXAS1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL9498067 | 0.75 | TAAR1 (0.61) | TAAR1SMN1; SMN2ALDH1A1FAAHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221601-B1 | [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-10 | — | — | EP | disclosed |
| US-5180832-A | Chemical intermediate for thromboxane A2 inhibitor | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-19 | — | — | US | disclosed |
| US-4963573-A | INHIBIT BIOSYNTHESIS OF THROMBOXANE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-10-16 | — | — | US | disclosed |
| US-4746671-A | THROMBOXANE SYNTHETASE INHIBITION | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-05-24 | — | — | US | disclosed |
| EP-0221601-A1 | [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-05-13 | — | — | EP | disclosed |