Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.61 |
| ▸ | MAPT | P10636 | 11/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647033 | 0.82 | MCL1 (0.65) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2610250 | 0.81 | RXFP1 (0.61) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL649968 | 0.81 | LIMK1 (0.68) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11074064 | 0.81 | LIMK1 (0.68) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14159248 | 0.81 | MAOB (0.61) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31347574 | 0.80 | MAPK1 (0.71) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4651653 | 0.80 | MAPK1 (0.71) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2503631 | 0.79 | PTGS2 (0.56) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2610241 | 0.79 | MCL1 (0.71) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15766514 | 0.79 | LIMK1 (0.71) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113501806-B | Chalcone-based fluorescent probe and preparation method and application thereof | 深圳大学 | 2022-06-28 | — | — | CN | claimed |
| CN-113501806-B | Chalcone-based fluorescent probe and preparation method and application thereof | 深圳大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-109790191-B | Platinum complexes and methods of use thereof | 香港大学 | 2022-04-08 | — | — | CN | disclosed |
| US-10672999-B2 | Gold complexes for OLED applications | THE UNIVERSITY OF HONG KONG (HK) | 2020-06-02 | — | — | US | disclosed |
| WO-2018024172-A1 | PLATINUM COMPLEXES AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2018-02-08 | — | — | WO | disclosed |
| US-20160301020-A1 | GOLD COMPLEXES FOR OLED APPLICATIONS | UNIV HONG KONG (HK) | 2016-10-13 | — | — | US | disclosed |
| EP-0279263-B1 | INDOLE, BENZOFURAN, BENZOTHIOPHENE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4873259-A | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0279263-A2 | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | disclosed |
| US-4260776-A | PYRAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160301020-A1 | GOLD COMPLEXES FOR OLED APPLICATIONS | OSBPL3, OSBP, OCIAD1 | RAB9A 1101/4885MAPT 334/4885KMT2A 3927/4885 |
| US-10672999-B2 | Gold complexes for OLED applications | OSBPL3, OSBP, OCIAD1 | RAB9A 1101/4885MAPT 334/4885KMT2A 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.