SCHEMBL647033

SCHEMBL647033

O=C(O)c1sc2ccccc2c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.65
MAOB P27338 4/20 0.58
RAB9A P51151 7/20 0.56
MAPT P10636 6/20 0.56
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
KDM4E B2RXH2 4/20 0.56
NFKB1 P19838 2/20 0.56
NFKB2 Q00653 2/20 0.56
RELA Q04206 2/20 0.56
ALDH1A1 P00352 1/20 0.56
MAOA P21397 1/20 0.54
NPC1 O15118 5/20 0.50
GAA P10253 3/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.50
GPR35 Q9HC97 1/20 0.50
PRNP P04156 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4604503 0.83 MAOB (0.77) MCL1MAOBRAB9AMAPTMEN1
SCHEMBL11074064 0.82 LIMK1 (0.68) MCL1MAOBRAB9AMAPTMEN1
SCHEMBL649968 0.82 LIMK1 (0.68) MCL1MAOBRAB9AMAPTMEN1
SCHEMBL9601620 0.82 RAB9A (0.61) MCL1MAOBRAB9AMAPTMEN1
SCHEMBL14159248 0.82 MAOB (0.61) MCL1MAOBRAB9AMAPTMEN1
Hydrochloric Acid SCHEMBL11077705 0.81 LIMK1 (0.66) MCL1MAOBRAB9AMAPTMEN1
SCHEMBL941112 0.80 MCL1 (0.65) MCL1MAPTMEN1KMT2AKDM4E
SCHEMBL29664668 0.80 MCL1 (0.65) MCL1MAPTMEN1KMT2AKDM4E
SCHEMBL9660830 0.79 RAB9A (0.58) MAOBRAB9AMAPTMEN1KMT2A
SCHEMBL1919937 0.78 LIMK1 (0.73) MCL1MAOBMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107635676-B Pretreatment method for electroless plating 麦克德米德股份有限公司 2020-09-18 CN claimed
US-20160348245-A1 Method of Pretreatment for Electroless Plating MACDERMID, INCORPORATED 2016-12-01 US claimed
EP-1685121-B1 ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2008-06-11 EP claimed
CN-107635676-B Pretreatment method for electroless plating 麦克德米德股份有限公司 2020-09-18 CN disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
EP-3297772-A1 METHOD OF PRETREATMENT FOR ELECTROLESS PLATING MacDermid, Incorporated (US) 2018-03-28 EP disclosed
US-20160348245-A1 Method of Pretreatment for Electroless Plating MACDERMID, INCORPORATED 2016-12-01 US disclosed
US-9174964-B2 AMPK-activating piperidinyloxy-substituted 2,3-dihydro-1H-indene-1-amine compounds and pharmaceutical compositions including the same RIGEL PHARMACEUTICALS, INC. (US) 2015-11-03 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-4933399-A COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-06-12 US disclosed
EP-0320227-A2 Method of preventing polymer-scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1989-06-14 EP disclosed
EP-0139464-B1 BENZOTHIOPHENE DERIVATES AS BRONCHODILATORS ELI LILLY AND COMPANY (US) 1988-10-19 EP disclosed
US-4703053-A Benzothiophenes and benzofurans and antiallergic use thereof WARNER-LAMBERT COMPANY (US) 1987-10-27 US disclosed
EP-0187487-A1 Benzothiophenes and benzofurans having antiallergic activity WARNER-LAMBERT COMPANY (US) 1986-07-16 EP disclosed
US-4552891-A BRONCHODILATOR ELI LILLY AND COMPANY (US) 1985-11-12 US disclosed
EP-0139464-A1 Benzothiophene derivates as bronchodilators ELI LILLY AND COMPANY (US) 1985-05-02 EP disclosed
US-3989718-A ANTIMICROBIAL ELI LILLY AND COMPANY (US) 1976-11-02 US disclosed
US-3989718-A ANTIMICROBIAL ELI LILLY AND COMPANY (US) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B MCL1 4700/4885MAOB 1170/4885RAB9A 2091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.