Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15653163 | 0.80 | CYP2B6 (0.40) | KCNN4ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL8443085 | 0.69 | CYP11B1 (0.36) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL2392374 | 0.68 | KCNN4 (0.69) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL1563373 | 0.67 | HSP90AA1 (0.47) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL27838424 | 0.66 | CYP11B1 (0.33) | KCNN4KCNA3CYP11B1CYP11B2 | |
| SCHEMBL8443367 | 0.65 | CYP11B1 (0.40) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL7982989 | 0.65 | CYP11B1 (0.40) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| Ammonia Solution, Strong SCHEMBL27402390 | 0.65 | HSP90AA1 (0.46) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL27902583 | 0.64 | ALDH1A1 (0.39) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL7254281 | 0.64 | GAA (0.48) | KCNN4KCNA3CYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702684-A | Iodine functionalized metal organic framework and preparation method and application thereof | 福州大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-104086528-A | Novel heterocyclic compounds as pesticides | BAYER IP GMBH | 2014-10-08 | — | — | CN | disclosed |
| CN-103140483-A | novel heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG | 2013-06-05 | — | — | CN | disclosed |
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |