Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602007 | 0.69 | KCNN4 (0.38) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL7982989 | 0.68 | CYP11B1 (0.40) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL1563373 | 0.65 | HSP90AA1 (0.47) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL1197948 | 0.65 | CYP11B1 (0.37) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL198143 | 0.65 | NOTUM (0.45) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL7796676 | 0.65 | CYP11B1 (0.46) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL2204870 | 0.64 | CYP11B1 (0.48) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL8443367 | 0.64 | CYP11B1 (0.40) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL2036810 | 0.64 | CYP11B1 (0.36) | CYP11B1CYP11B2KCNN4KCNA3TSHR | |
| SCHEMBL2392374 | 0.63 | KCNN4 (0.69) | CYP11B1CYP11B2KCNN4KCNA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594263-B1 | INTERMEDIATES FOR THE PREPARATION OF THIOALKYLTHIO CEPHALOSPORIN DERIVATIVES | SHIONOGI & CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| CN-1034504-C | Thioalkylthio cephalosporin derivatives | SHIONOGI & CO (JP) | 1997-04-09 | — | — | CN | disclosed |
| US-5352792-A | Bactericides | SHIONOGI & CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0467647-B1 | Thioalkylthio cephalosporin derivatives | SHIONOGI & CO (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0594263-A1 | Thioalkylthio cephalosporin derivatives and intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-5214037-A | Antibiotic, bactericide | SHIONOGI & CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0467647-A2 | Thioalkylthio cephalosporin derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |