Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | CSF1R | P07333 | 1/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.57 |
| ▸ | MET | P08581 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.57 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823318 | 0.89 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2AURKAABL1 | |
| SCHEMBL803150 | 0.88 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2AURKAABL1 | |
| SCHEMBL8452469 | 0.84 | SMN1; SMN2 (0.62) | NPC1RAB9ASMN1; SMN2AURKAABL1 | |
| SCHEMBL12684741 | 0.83 | RAB9A (0.63) | NPC1RAB9ASMN1; SMN2AURKAABL1 | |
| SCHEMBL10561342 | 0.83 | SMN1; SMN2 (0.63) | NPC1RAB9ASMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL15304176 | 0.82 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2AURKAABL1 | |
| SCHEMBL4796772 | 0.82 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2AURKAABL1 | |
| SCHEMBL21035639 | 0.81 | CYP11B1 (0.54) | NPC1RAB9ASMN1; SMN2AURKAABL1 | |
| SCHEMBL2216313 | 0.81 | FYN (0.56) | NPC1RAB9ASMN1; SMN2AURKAABL1 | |
| SCHEMBL4943133 | 0.81 | SMN1; SMN2 (0.62) | NPC1RAB9ASMN1; SMN2TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62138471-A | — | — | None | — | — | JP | disclosed |
| US-5262084-A | Visual aids | CHISSO CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0364588-B1 | LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1993-02-10 | — | — | EP | disclosed |
| JP-S62138471-A | PYRIDINE DERIVATIVE | CHISSO CORP | 1987-06-22 | — | — | JP | disclosed |