Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158442 | 0.82 | TSHR (0.65) | TSHRSMN1; SMN2RECQLHTTLMNA | |
| SCHEMBL13632337 | 0.81 | HPGD (0.67) | TSHRSMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL28722945 | 0.81 | ACACB (0.56) | TSHRSMN1; SMN2LMNAALDH1A1L3MBTL1 | |
| SCHEMBL11961203 | 0.79 | ALDH1A1 (0.56) | TSHRHTTLMNAALDH1A1HPGD | |
| SCHEMBL20405434 | 0.79 | ALDH1A1 (0.61) | TSHRSMN1; SMN2RECQLHTTLMNA | |
| SCHEMBL2077743 | 0.78 | TSHR (0.60) | TSHRSMN1; SMN2RECQLHTTLMNA | |
| SCHEMBL13821653 | 0.78 | TSHR (0.60) | TSHRSMN1; SMN2RECQLHTTLMNA | |
| SCHEMBL2077746 | 0.78 | TSHR (0.65) | TSHRSMN1; SMN2RECQLHTTLMNA | |
| SCHEMBL11184712 | 0.77 | ALDH1A1 (0.72) | TSHRSMN1; SMN2RECQLHTTLMNA | |
| SCHEMBL7977181 | 0.76 | TSHR (0.58) | TSHRSMN1; SMN2RECQLHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206415-B1 | (4-PIPERIDINYLMETHYL AND -HETERO)PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-27 | — | — | EP | claimed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |