Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.56 |
| ▸ | ACACA | Q13085 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602337 | 0.81 | TSHR (0.57) | MAPK1LMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL6185165 | 0.81 | MAPK1 (0.53) | ACACBACACAMAPK1LMNACYP1A2 | |
| SCHEMBL6185328 | 0.81 | MAPK1 (0.53) | ACACBACACAMAPK1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL4295644 | 0.80 | MAPK1 (0.52) | ACACBACACAMAPK1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL4300948 | 0.80 | MAPK1 (0.52) | ACACBACACAMAPK1LMNACYP1A2 | |
| SCHEMBL6183048 | 0.76 | RECQL (0.70) | ACACBACACAMAPK1LMNACYP1A2 | |
| SCHEMBL1306587 | 0.74 | SMN1; SMN2 (0.44) | ACACBACACALMNAALDH1A1KDM4E | |
| SCHEMBL976549 | 0.73 | ACACB (1.00) | ACACBACACAADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL6182411 | 0.73 | ACACB (0.66) | ACACBACACAALDH1A1KDM4EADRA1A | |
| SCHEMBL3459079 | 0.73 | ACACB (1.00) | ACACBACACAADRA1AL3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715637-B | Glucokinase activators and methods of use thereof | 百时美施贵宝公司 | 2022-04-05 | — | — | CN | disclosed |