Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602431 | 0.74 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL24524725 | 0.65 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL23555977 | 0.65 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL23555976 | 0.65 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL6846988 | 0.65 | SPHK1 (0.39) | MAPT | |
| SCHEMBL19973666 | 0.65 | SPHK1 (0.39) | MAPT | |
| SCHEMBL6882185 | 0.65 | PPM1B (0.38) | ALDH1A1MAPT | |
| SCHEMBL4472058 | 0.65 | PPM1B (0.38) | ALDH1A1MAPT | |
| SCHEMBL8427865 | 0.65 | SPHK1 (0.39) | MAPT | |
| SCHEMBL6882437 | 0.65 | PPM1B (0.38) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217963-A | Antiischemic, antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5057506-A | Anticonvulsants, antispasmodic and antischemic agents | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| US-4906621-A | Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4898854-A | NERVOUS SYSTEM DISORDERS | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |