Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 4/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266776 | 0.81 | HTR3A (0.55) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9601383 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7429564 | 0.80 | HTR3A (0.54) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL7385250 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9602256 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL7383321 | 0.75 | HTR3A (0.51) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL4102887 | 0.73 | NOTUM (0.47) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL4630078 | 0.73 | NOTUM (0.47) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9602248 | 0.71 | MEN1 (0.43) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9531967 | 0.70 | HTR3A (0.57) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |