Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 15/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602465 | 1.00 | TBXAS1 (0.69) | TBXAS1TBXA2RLMNATDP1CYP1A2 | |
| Oxalic Acid SCHEMBL9600622 | 0.85 | TBXAS1 (0.60) | TBXAS1TBXA2RLMNATDP1CYP1A2 | |
| Oxalic Acid SCHEMBL9600632 | 0.85 | TBXAS1 (0.60) | TBXAS1TBXA2RLMNATDP1CYP1A2 | |
| Oxalic Acid SCHEMBL9600638 | 0.85 | TBXAS1 (0.60) | TBXAS1TBXA2RLMNATDP1CYP1A2 | |
| SCHEMBL10659433 | 0.84 | TBXAS1 (0.93) | TBXAS1TBXA2RLMNA | |
| SCHEMBL9601366 | 0.81 | TBXAS1 (0.85) | TBXAS1TBXA2R | |
| SCHEMBL9601354 | 0.81 | TBXAS1 (0.85) | TBXAS1TBXA2R | |
| SCHEMBL9601397 | 0.76 | TBXAS1 (0.74) | TBXAS1TBXA2RLMNA | |
| SCHEMBL9601393 | 0.76 | TBXAS1 (0.74) | TBXAS1TBXA2RLMNA | |
| SCHEMBL9601416 | 0.75 | TBXAS1 (0.74) | TBXAS1TBXA2RCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221601-B1 | [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-10 | — | — | EP | disclosed |
| US-5180832-A | Chemical intermediate for thromboxane A2 inhibitor | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-19 | — | — | US | disclosed |
| US-4963573-A | INHIBIT BIOSYNTHESIS OF THROMBOXANE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-10-16 | — | — | US | disclosed |
| US-4746671-A | THROMBOXANE SYNTHETASE INHIBITION | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-05-24 | — | — | US | disclosed |
| EP-0221601-A1 | [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-05-13 | — | — | EP | disclosed |