Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.93 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601354 | 0.95 | TBXAS1 (0.85) | TBXAS1TBXA2R | |
| SCHEMBL9601366 | 0.95 | TBXAS1 (0.85) | TBXAS1TBXA2R | |
| SCHEMBL9601416 | 0.89 | TBXAS1 (0.74) | TBXAS1TBXA2R | |
| SCHEMBL9601423 | 0.89 | TBXAS1 (0.74) | TBXAS1TBXA2R | |
| SCHEMBL9601393 | 0.88 | TBXAS1 (0.74) | TBXAS1TBXA2RLMNA | |
| SCHEMBL9601397 | 0.88 | TBXAS1 (0.74) | TBXAS1TBXA2RLMNA | |
| SCHEMBL9602465 | 0.84 | TBXAS1 (0.69) | TBXAS1TBXA2RLMNA | |
| SCHEMBL9602469 | 0.84 | TBXAS1 (0.69) | TBXAS1TBXA2RLMNA | |
| SCHEMBL9601778 | 0.84 | TBXAS1 (0.70) | TBXAS1TBXA2R | |
| SCHEMBL9601773 | 0.84 | TBXAS1 (0.70) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746671-A | THROMBOXANE SYNTHETASE INHIBITION | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-05-24 | — | — | US | disclosed |