Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602793 | 0.81 | FDPS (0.40) | FDPSBTN3A1PDE3ALMNACYP1A2 | |
| SCHEMBL4197085 | 0.79 | FDPS (0.47) | FDPSBTN3A1PDE3ALMNACYP1A2 | |
| SCHEMBL15533205 | 0.77 | FDPS (0.53) | FDPSBTN3A1PDE3ALMNACYP1A2 | |
| SCHEMBL4725467 | 0.75 | FDPS (0.51) | FDPSBTN3A1PDE3ALMNACYP1A2 | |
| SCHEMBL8389732 | 0.74 | FDPS (0.46) | FDPSBTN3A1PDE3ALMNACYP1A2 | |
| SCHEMBL9850885 | 0.73 | LMNA (0.51) | FDPSBTN3A1PDE3ALMNACYP1A2 | |
| SCHEMBL6777278 | 0.72 | LMNA (0.42) | FDPSBTN3A1PDE3ALMNACYP1A2 | |
| Water SCHEMBL29532583 | 0.71 | LMNA (0.50) | FDPSBTN3A1PDE3ALMNACYP1A2 | |
| SCHEMBL8768063 | 0.71 | SMN1; SMN2 (0.43) | FDPS | |
| SCHEMBL8389091 | 0.71 | FDPS (0.40) | FDPSBTN3A1PDE3ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217963-A | Antiischemic, antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5057506-A | Anticonvulsants, antispasmodic and antischemic agents | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0203891-B1 | CERTAIN PHOSPHONIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-05-15 | — | — | EP | disclosed |
| US-4898854-A | NERVOUS SYSTEM DISORDERS | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0203891-A2 | Certain phosphonic acids and derivatives | CIBA-GEIGY AG (CH) | 1986-12-03 | — | — | EP | disclosed |