Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601289 | 0.73 | TAAR1 (0.35) | MGMTPNPTSHR | |
| SCHEMBL13280659 | 0.60 | TSHR (0.41) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2463738 | 0.57 | MAPT (0.35) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL43101 | 0.57 | — | — | |
| SCHEMBL17033080 | 0.56 | ALDH1A1 (0.40) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8146532 | 0.56 | ALDH1A1 (0.54) | GAAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1404275 | 0.56 | CHRM2 (0.46) | GAAKDM4EMEN1ALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL28482817 | 0.55 | — | — | |
| Hydrochloric Acid SCHEMBL2389399 | 0.55 | — | — | |
| Furfuryl Alcohol SCHEMBL1308222 | 0.55 | ADORA2A (0.43) | GAAKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206415-B1 | (4-PIPERIDINYLMETHYL AND -HETERO)PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-27 | — | — | EP | disclosed |