SCHEMBL96029

SCHEMBL96029

O=[C]Cc1ccc(F)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.48
IDO1 P14902 3/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
MAOB P27338 1/20 0.41
MIF P14174 1/20 0.41
AGXT P21549 2/20 0.41
DAO P14920 1/20 0.38
FFAR1 O14842 1/20 0.38
GAA P10253 1/20 0.38
PLA2G1B P04054 1/20 0.37
ATG4B Q9Y4P1 1/20 0.37
LMNA P02545 1/20 0.37
PYCR1 P32322 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11139354 0.86 CYP3A4 (0.42)
SCHEMBL18244863 0.79 IDO1 (0.46) TAAR1IDO1LOXL2MAOBMIF
SCHEMBL18427888 0.78 HRH3 (0.41) TAAR1MAOBFFAR1GAALMNA
SCHEMBL7128264 0.75 HTT (0.42) MAOBDAO
SCHEMBL980506 0.75 TAAR1 (0.50) TAAR1IDO1LOXL2MAOBMIF
SCHEMBL910567 0.74 ESR1 (0.57) TAAR1IDO1LMNA
SCHEMBL37742 0.74 IDO1 (0.46) TAAR1IDO1LOXL2MAOBMIF
SCHEMBL3736025 0.74 TAAR1 (0.48) TAAR1IDO1MAOBPYCR1
SCHEMBL3633726 0.74 MIF (0.52) TAAR1IDO1LOXL2MAOBMIF
SCHEMBL8625033 0.74 HRH3 (0.50) TAAR1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310539-A1 TREATMENT OF DISEASE WITH EPOR ANTAGONIST EPO-MED INC. (JP) 2023-10-05 US claimed
EP-4190345-A1 TREATMENT OF DISEASE WITH EPOR ANTAGONIST Epo-Med Inc. (JP) 2023-06-07 EP claimed
CN-116234541-A Treatment of diseases by EpoR antagonists EPO医药株式会社 2023-06-06 CN claimed
CN-113166203-A Anti-erythropoietin receptor peptides EPO医药株式会社 2021-07-23 CN claimed
EP-3851448-A1 ANTI-ERYTHROPOIETIN RECEPTOR PEPTIDE EPO-Med Inc. (JP) 2021-07-21 EP claimed
WO-2020054813-A1 ANTI-ERYTHROPOIETIN RECEPTOR PEPTIDE エポメッド株式会社 2020-03-19 WO claimed
WO-2017013593-A1 ISOQUINOLINONE DERIVATIVES AS PARP INHIBITORS LUPIN LIMITED (IN) 2017-01-26 WO claimed
EP-2501685-A1 [1,5]-DIAZOCIN DERIVATIVES Mellitech (FR) 2012-09-26 EP claimed
WO-2011058193-A1 [1,5]-DIAZOCIN DERIVATIVES MELLITECH (FR) 2011-05-19 WO claimed
US-7666866-B2 Antithrombotic diamides ELI LILLY AND COMPANY (US) 2010-02-23 US claimed
EP-0469887-A1 Acetamide derivatives ZENECA LIMITED (GB) 1992-02-05 EP claimed
US-5068222-A Polypeptides for treatment of cancer IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-11-26 US claimed
US-5049551-A Antitumor UBE INDUSTRIES, LTD. (JP) 1991-09-17 US claimed
EP-0480918-A4 REDUCED SIZE LHRH ANALOGS. ABBOTT LAB (US) 1991-06-04 EP claimed
EP-0417454-A2 Reduced size LHRH analogs ABBOTT LABORATORIES (US) 1991-03-20 EP claimed
EP-0400610-A1 5-Fluorouracil derivatives UBE INDUSTRIES, LTD. (JP) 1990-12-05 EP claimed
WO-1989007451-A1 REDUCED SIZE LHRH ANALOGS ABBOTT LABORATORIES (US) 1989-08-24 WO claimed
EP-0328089-A2 Reduced size LHRH analogs ABBOTT LABORATORIES (US) 1989-08-16 EP claimed
EP-0315367-A2 Polypeptides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-10 EP claimed
EP-0142146-B1 OXO-ANALOGS OF MEVINOLIN-LIKE ANTIHYPERCHOLESTEROLEMIC AGENTS MERCK & CO. INC. (US) 1988-08-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310539-A1 TREATMENT OF DISEASE WITH EPOR ANTAGONIST EPOR, PROKR1, HBZ TAAR1 1902/4885IDO1 4593/4885LOXL2 2562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.