Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139354 | 0.86 | CYP3A4 (0.42) | ESR1ESR2ALDH1A1KMT2ATDP1 | |
| SCHEMBL243411 | 0.79 | TSHR (0.43) | CA2CA12CA1CYP3A4TYR | |
| SCHEMBL16904622 | 0.78 | ESR1 (0.55) | ESR1ESR2KDM4EALDH1A1HTR1A | |
| SCHEMBL18427888 | 0.78 | HRH3 (0.41) | TAAR1CA2CA12CA1LMNA | |
| SCHEMBL7103399 | 0.77 | ESR1 (0.70) | ESR1ESR2KDM4EALDH1A1HTR1A | |
| SCHEMBL8023647 | 0.75 | PGK1 (0.36) | ESR1ESR2ALDH1A1CYP2C19BLM | |
| SCHEMBL582045 | 0.75 | ESR1 (0.59) | ESR1ESR2KDM4EALDH1A1HTR1A | |
| SCHEMBL96029 | 0.74 | TAAR1 (0.48) | TAAR1IDO1LMNA | |
| SCHEMBL465580 | 0.74 | TAAR1 (0.48) | SLC6A2CYP2C19TAAR1KMT2AIDO1 | |
| SCHEMBL8625033 | 0.74 | HRH3 (0.50) | TAAR1CA2ABATCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11738087-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2023-08-29 | — | — | US | claimed |
| CN-101967094-B | Phenylacetyl quinic acid of witlooves and ester compound thereof | LI GUOYU | 2013-06-19 | — | — | CN | claimed |
| US-20120277164-A1 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2012-11-01 | — | — | US | claimed |
| EP-2491051-A2 | GADD45BETA TARGETING AGENTS | Imperial Innovations Limited (GB) | 2012-08-29 | — | — | EP | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| CN-101967094-A | Phenylacetyl quinic acid of witlooves and ester compound thereof | GUOYU LI | 2011-02-09 | — | — | CN | claimed |
| EP-2210900-A2 | Analogues of GLP-1 | IPSEN PHARMA (FR) | 2010-07-28 | — | — | EP | claimed |
| US-20090300800-A1 | D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation | BASF PLANT SCIENCE GMBH (DE) | 2009-12-03 | — | — | US | claimed |
| EP-1711523-A4 | ANALOGUES OF GLP-1 | SOD CONSEILS RECH APPLIC (FR) | 2008-05-21 | — | — | EP | claimed |
| US-20070248996-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | PARAECIS PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | US | claimed |
| US-4533495-A | Method of producing 2-azetidinone-1-sulfonic acid compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-08-06 | — | — | US | claimed |
| EP-0082568-B1 | RETRO-INVERSO ANALOGUES OF C-TERMINAL PENTA AND HEXAPEPTIDES OF SUBSTANCE P. | ANIC S.p.A. (IT) | 1984-11-21 | — | — | EP | claimed |
| US-4439360-A | Retro-inverso analogues of C-terminal penta and hexapeptides of Substance P | ANIC S.P.A. (IT) | 1984-03-27 | — | — | US | claimed |
| US-4401660-A | TYLOSINS; VETERINARY MEDICINE; PASTEURELLA; ANIMAL GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1983-08-30 | — | — | US | claimed |
| EP-0082568-A2 | Retro-inverso analogues of C-terminal penta and hexapeptides of substance P. | ANIC S.p.A. (IT) | 1983-06-29 | — | — | EP | claimed |
| EP-0000931-B1 | ENZYMATIC CLEAVAGE OF N-ACYL-THIENAMYCINS | MERCK & CO. INC. (US) | 1982-04-14 | — | — | EP | claimed |
| US-4162193-A | Enzymatic cleavage of N-acyl-thienamycins | MERCK & CO., INC. (US) | 1979-07-24 | — | — | US | claimed |
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | claimed |
| EP-0000931-A1 | Enzymatic cleavage of N-acyl-thienamycins | MERCK & CO. INC. (US) | 1979-03-07 | — | — | EP | claimed |
| US-3972774-A | BY AN ESTERASE ENZYME FROM BACILLUS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248996-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | APP, IAPP, BACE1 | ESR1 3309/4885ESR2 1939/4885KDM4E 3643/4885 |
| US-11738087-B2 | Lymph directing prodrugs | MLNR, ABCB11, MLN | ESR1 1417/4885ESR2 2975/4885KDM4E 1955/4885 |
| US-20120277164-A1 | GADD45BETA TARGETING AGENTS | DDB1, CCL2, DDIT3 | ESR1 3378/4885ESR2 2174/4885KDM4E 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.