Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | DRD2 | P14416 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bmy-14802 SCHEMBL8457738 | 0.88 | SIGMAR1 (1.00) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| Hydrochloric Acid SCHEMBL9603075 | 0.88 | SLC6A2 (0.64) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| Bmy-14802 SCHEMBL467229 | 0.88 | SIGMAR1 (1.00) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| Bmy-14802 SCHEMBL466842 | 0.87 | SIGMAR1 (0.97) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| Bmy-14802 SCHEMBL10843594 | 0.87 | SIGMAR1 (0.97) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| SCHEMBL5023694 | 0.85 | DRD2 (0.65) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| SCHEMBL9766050 | 0.84 | SIGMAR1 (0.71) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| SCHEMBL9765987 | 0.84 | SIGMAR1 (0.75) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| Hydrochloric Acid SCHEMBL9766034 | 0.83 | SIGMAR1 (0.74) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| SCHEMBL13532633 | 0.82 | SIGMAR1 (0.84) | SIGMAR1KDM4ECYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308476-B1 | BISPHENYLALKYLPIPERAZINE DERIVATIVES, A METHOD OF THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Kabi Pharmacia AB (SE) | 1993-02-03 | — | — | EP | disclosed |
| US-4937245-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | FEX TOMAS (SE) | 1990-06-26 | — | — | US | disclosed |