Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604441 | 0.83 | MTNR1A (0.59) | GAALMNAALDH1A1HPGDMTNR1A | |
| SCHEMBL9790435 | 0.81 | MTNR1A (0.57) | GAALMNAALDH1A1HPGDMTNR1A | |
| SCHEMBL9790430 | 0.81 | MTNR1A (0.57) | GAALMNAALDH1A1HPGDMTNR1A | |
| SCHEMBL9790439 | 0.81 | MTNR1A (0.57) | GAALMNAALDH1A1HPGDMTNR1A | |
| SCHEMBL2148188 | 0.80 | GAA (0.63) | GAALMNAALDH1A1HPGDERCC1 | |
| SCHEMBL22322799 | 0.79 | MTNR1A (0.54) | GAALMNAALDH1A1HPGDMTNR1A | |
| SCHEMBL83922 | 0.78 | HPGD (0.86) | GAALMNAALDH1A1HPGDNPC1 | |
| SCHEMBL9769939 | 0.78 | GAA (0.61) | GAALMNAALDH1A1HPGDMTNR1A | |
| SCHEMBL27567042 | 0.77 | GAA (0.59) | GAALMNAALDH1A1HPGDERCC1 | |
| SCHEMBL9665775 | 0.77 | GAA (0.59) | GAALMNAALDH1A1HPGDERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |