SCHEMBL83922

SCHEMBL83922

C=CCNC(=O)c1ccccc1

nearest known ligand 0.86

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.86
ALDH1A1 P00352 3/20 0.86
LMNA P02545 2/20 0.86
MAPT P10636 3/20 0.69
SMN1; SMN2 Q16637 2/20 0.68
POLB P06746 1/20 0.68
RAB9A P51151 3/20 0.63
PKM P14618 2/20 0.62
GAA P10253 2/20 0.61
CYP1A2 P05177 2/20 0.59
KDM4E B2RXH2 2/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
NPC1 O15118 1/20 0.56
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4800405 0.93 HPGD (1.00) HPGDALDH1A1LMNAMAPTSMN1; SMN2
Thiosulfuric Acid SCHEMBL11090512 0.90 HPGD (0.71) HPGDALDH1A1LMNAMAPTSMN1; SMN2
Thiosulfuric Acid SCHEMBL11090513 0.90 HPGD (0.71) HPGDALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL2385213 0.90 HPGD (0.76) HPGDALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL7110355 0.86 HPGD (0.67) HPGDALDH1A1LMNAMAPTSMN1; SMN2
Piperidine SCHEMBL11302904 0.86 HPGD (0.66) HPGDALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL4970119 0.85 LMNA (0.66) HPGDALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL4049341 0.85 LMNA (0.69) HPGDALDH1A1LMNAMAPTSMN1; SMN2
Anthranilic Acid SCHEMBL28965727 0.84 HPGD (0.64) HPGDALDH1A1LMNAMAPTSMN1; SMN2
Pyrazole SCHEMBL19244888 0.83 HPGD (0.62) HPGDALDH1A1LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023177842-A1 COPPER-CATALYZED AMIDATION OF POLYOLEFINS BASF CORPORATION (US) 2023-09-21 WO claimed
CN-114642210-A Suspending agent containing methoxy carbamate and cyazofamid and application thereof 山东统防生物科技有限公司 2022-06-21 CN claimed
CN-110511521-B Polyallylbenzamide-graphene hydrogel and preparation method thereof 吉林省七维生物科技有限公司 2021-12-14 CN claimed
CN-108473429-B ROR gamma modulators 领先制药控股公司 2021-09-10 CN claimed
CN-107915718-B N-acyl alkyl benzoyl amide compound with insecticidal activity and application thereof 江苏中旗科技股份有限公司 2021-04-02 CN claimed
CN-112441987-A Synthesis method of halogen oxazoline compound 商丘师范学院 2021-03-05 CN claimed
US-10927283-B2 Friction-reducing compositions for use in drilling operations EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-23 US claimed
CN-110194739-B Cyanoalkyl substituted dihydroisoquinolinone compound and preparation method thereof 江苏理工学院 2020-12-08 CN claimed
EP-3472174-B1 METHOD FOR THE PREPARATION OF SUBSTITUTED THIOLACTONES, NEW SUBSTITUTED THIOLACTONES, AND USES THEREOF CENTRE NAT RECH SCIENT (FR) 2020-11-18 EP claimed
US-10774092-B2 ULK1 inhibitors and methods using same SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2020-09-15 US claimed
EP-0102318-B1 PREPARATION OF BETA-AMINO-ALPHA,BETA-UNSATURATED CARBOXYLIC-ACID ESTERS CIBA-GEIGY AG (CH) 1987-01-14 EP claimed
EP-0055562-B1 CEPHALOSPORIN DERIVATIVES ICI PHARMA (FR) 1986-02-12 EP claimed
US-4540650-A Photoresists suitable for forming relief structures of highly heat-resistant polymers MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-09-10 US claimed
US-4496560-A ACTIVE AGAINST GRAMPOSITIVE BACTERIA RHONE-POULENC SANTE (FR) 1985-01-29 US claimed
US-4492692-A BACTERICIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-01-08 US claimed
EP-0055099-B1 PENICILLIN DERIVATIVES ICI PHARMA (FR) 1984-10-24 EP claimed
EP-0097353-A2 Improved process for interferon production THE WELLCOME FOUNDATION LIMITED (GB) 1984-01-04 EP claimed
EP-0075434-A2 Cephalosporins, their preparation and their pharmaceutical compositions ICI PHARMA (FR) 1983-03-30 EP claimed
EP-0071370-A2 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them ICI PHARMA (FR) 1983-02-09 EP claimed
EP-0055099-A1 Penicillin derivatives ICI PHARMA (FR) 1982-06-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10774092-B2 ULK1 inhibitors and methods using same ULK1, ULK2, ULK3 HPGD 3505/4885ALDH1A1 4159/4885LMNA 4086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.