⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31251666 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL961904 | 0.98 | KMT2A (0.50) | — | |
| SCHEMBL2912518 | 0.81 | KDR (0.57) | — | |
| SCHEMBL307846 | 0.79 | — | — | |
| SCHEMBL30496405 | 0.79 | — | — | |
| SCHEMBL18469872 | 0.77 | — | — | |
| SCHEMBL10138664 | 0.77 | — | — | |
| SCHEMBL21241163 | 0.76 | KMT2A (0.50) | — | |
| SCHEMBL1759892 | 0.74 | GOT1 (0.37) | — | |
| SCHEMBL8599391 | 0.74 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735430-A1 | MALT1 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025003414-A1 | MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-02 | — | — | WO | disclosed |
| US-20240425480-A1 | NOVEL PYRIDINE DERIVATIVE COMPOUND AS RON INHIBITOR | LG CHEM, LTD. (KR) | 2024-12-26 | — | — | US | disclosed |
| US-20240317739-A1 | NOVEL UREA DERIVATIVE COMPOUND AS RON INHIBITOR | LG CHEM, LTD. (KR) | 2024-09-26 | — | — | US | disclosed |
| WO-2024153208-A9 | MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2024-08-22 | — | — | WO | disclosed |
| WO-2024153208-A1 | MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2024-07-25 | — | — | WO | disclosed |
| EP-4349825-A1 | NOVEL PYRIDINE DERIVATIVE COMPOUND AS RON INHIBITOR | LG Chem, Ltd. (KR) | 2024-04-10 | — | — | EP | disclosed |
| EP-4339196-A1 | NOVEL UREA DERIVATIVE COMPOUND AS RON INHIBITOR | LG Chem, Ltd. (KR) | 2024-03-20 | — | — | EP | disclosed |
| CN-117500804-A | Novel urea derivative compounds as RON inhibitors | 株式会社LG化学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117396468-A | Novel pyridine derivative compounds as RON inhibitors | 株式会社LG化学 | 2024-01-12 | — | — | CN | disclosed |
| US-20020055635-A1 | Cycloalkano-indole and -azaindole derivatives | MULLER ULRICH (DE) | 2002-05-09 | — | — | US | disclosed |
| US-6265431-B1 | ANTICHOLESTEROL DRUGS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | disclosed |
| US-6245775-B1 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-12 | — | — | US | disclosed |
| CN-1050605-C | Cycloalkano-indole and-azaindole derivatives, process for preparing same and pharmaceutical composition containing same | BAYER AG (DE) | 2000-03-22 | — | — | CN | disclosed |
| CN-1224715-A | Cycloalkano-indote and againdole derivatives, process for their preparation and pharmaceutical composition containing the same | BAYER AG (DE) | 1999-08-04 | — | — | CN | disclosed |
| US-5684014-A | FOR TREATING ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |
| CN-1130631-A | Cycloalkano-indole and-azaindole derivatives | BAYER AG (DE) | 1996-09-11 | — | — | CN | disclosed |
| EP-0705831-A2 | Cycloalkano-indole- and -azaindole derivatives | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| US-4293553-A | ANTITHROMBOTIC AGENT | Ishikawa, Masayuki (JP) | 1981-10-06 | — | — | US | disclosed |
| US-3936444-A | FROM A LACTIM-ETHER AND AN ARYL OR HETEROARYL HYDRAZINE, ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |