Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597484 | 0.89 | HTR3A (0.39) | HTR3AHTR2CCYP1A2CYP3A4ADRA2C | |
| Maleic Acid SCHEMBL9597128 | 0.83 | PADI4 (0.36) | HTR3AHTR2CCYP1A2CYP3A4ADRA2C | |
| Fumaric Acid SCHEMBL9597136 | 0.83 | PADI4 (0.36) | HTR3AHTR2CCYP1A2CYP3A4ADRA2C | |
| SCHEMBL7408263 | 0.75 | KMT2A (0.43) | TP53HPGDHSD17B10SLC2A1 | |
| SCHEMBL23817260 | 0.74 | NR2E1 (0.41) | HTR2CCYP1A2TP53HPGDHSD17B10 | |
| SCHEMBL9366364 | 0.73 | HTR3A (0.35) | HTR3AHTR2CCYP1A2CYP3A4ADRA2C | |
| SCHEMBL10343 | 0.72 | CYP1A2 (0.63) | HTR3AHTR2CCYP1A2CYP3A4ADRA2C | |
| Iodide SCHEMBL7405172 | 0.72 | HPGD (0.41) | CYP1A2TP53HPGDHSD17B10SLC2A1 | |
| SCHEMBL9603272 | 0.72 | HTR3A (0.36) | HTR3AHTR2CCYP1A2CYP3A4ADRA2C | |
| SCHEMBL3994101 | 0.72 | CYP3A4 (0.62) | HTR3ACYP1A2CYP3A4HTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202343-A | Treating anxiety, psychological disorders | GLAXO GROUP LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |