Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807038 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRKDM4EALDH1A1MGAM | |
| SCHEMBL30979447 | 0.77 | ADRA2A (0.46) | SMN1; SMN2TSHRCSNK1A1TYRO3DYRK1B | |
| SCHEMBL3912410 | 0.77 | PDE10A (0.56) | SMN1; SMN2TSHRKDM4EALDH1A1MGAM | |
| SCHEMBL5458072 | 0.75 | DHODH (0.54) | SMN1; SMN2TSHRKDM4EALDH1A1IKBKB | |
| SCHEMBL7397500 | 0.74 | KDM4E (0.65) | SMN1; SMN2TSHRCSNK1A1TYRO3DYRK1B | |
| SCHEMBL6824177 | 0.74 | MTOR (0.54) | CSNK1A1TYRO3DYRK1BKDM4EALDH1A1 | |
| SCHEMBL8521039 | 0.73 | NPC1 (0.63) | SMN1; SMN2TSHRKDM4EALDH1A1MGAM | |
| SCHEMBL9065016 | 0.72 | TSHR (0.52) | SMN1; SMN2TSHRKDM4EALDH1A1NISCH | |
| SCHEMBL9804671 | 0.72 | MTOR (0.52) | SMN1; SMN2CSNK1A1TYRO3DYRK1BKDM4E | |
| SCHEMBL30965100 | 0.72 | CSNK1A1 (0.73) | TSHRCSNK1A1TYRO3DYRK1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61280404-A | — | — | None | — | — | JP | disclosed |
| EP-0537318-A1 | NEW NON-HYGROSCOPIC MONO-AMMONIUM SALTS. | ALKALOIDA VEGYESZETI GYAR (HU) | 1993-04-21 | — | — | EP | disclosed |
| WO-1992018513-A1 | NEW NON-HYGROSCOPIC MONO-AMMONIUM SALTS | ALKALOIDA VEGYÉSZETI GYÁR RT. (HU) | 1992-10-29 | — | — | WO | disclosed |
| JP-S61280404-A | HERBICIDAL COMPOSITION | SUMITOMO CHEM CO LTD | 1986-12-11 | — | — | JP | disclosed |