Sugi Predict

Sugi Predict / Compounds / SCHEMBL9603914

SCHEMBL9603914

SCHEMBL9603914

CC(C)(C)c1ccc2sc3c(-c4ccc(-c5nc6ccccc6o5)cc4)cc(C(C)(C)C)cc3c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 10/20 0.44
▸ RAB9A P51151 8/20 0.44
▸ GFER P55789 2/20 0.44
▸ TP53 P04637 3/20 0.43
▸ SMN1; SMN2 Q16637 6/20 0.42
▸ KDM4E B2RXH2 6/20 0.42
▸ ALDH1A1 P00352 6/20 0.42
▸ HPGD P15428 6/20 0.42
▸ MAPT P10636 5/20 0.42
▸ GAA P10253 2/20 0.42
▸ NFKB1 P19838 2/20 0.42
▸ NFKB2 Q00653 2/20 0.42
▸ RELA Q04206 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ STAT1 P42224 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ HSPD1 P10809 2/20 0.39
▸ PTPN2 P17706 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9603922 0.90 NPC1 (0.45) NPC1RAB9AGFERTP53SMN1; SMN2
SCHEMBL8281208 0.83 S1PR1 (0.45) NPC1RAB9ATP53SMN1; SMN2KDM4E
SCHEMBL9603897 0.82 NPC1 (0.48) NPC1RAB9AGFERTP53SMN1; SMN2
SCHEMBL9603921 0.81 NPC1 (0.46) NPC1RAB9AGFERTP53SMN1; SMN2
SCHEMBL8514091 0.81 NPC1 (0.46) NPC1RAB9AGFERTP53SMN1; SMN2
SCHEMBL9603907 0.80 NPC1 (0.48) NPC1RAB9AGFERTP53SMN1; SMN2
SCHEMBL9603933 0.80 NPC1 (0.45) NPC1RAB9AGFERTP53SMN1; SMN2
SCHEMBL9603927 0.80 NPC1 (0.45) NPC1RAB9AGFERTP53SMN1; SMN2
SCHEMBL9603994 0.80 NPC1 (0.49) NPC1RAB9AGFERTP53SMN1; SMN2
SCHEMBL9603909 0.79 NPC1 (0.47) NPC1RAB9AGFERTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device XDH, AOX1, CYP4X1 NPC1 4611/4885RAB9A 3002/4885GFER 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.