Sugi Predict

Sugi Predict / Compounds / SCHEMBL9603923

SCHEMBL9603923

SCHEMBL9603923

c1ccc2cc(-c3ccc(-c4ccc5sc6c(-c7ccc(-c8nc9ccccc9o8)cc7)cc(-c7ccc(-c8ccc9ccccc9c8)cc7)cc6c5c4)cc3)ccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 12/20 0.43
▸ RAB9A P51151 10/20 0.43
▸ ALDH1A1 P00352 8/20 0.43
▸ HPGD P15428 8/20 0.43
▸ KDM4E B2RXH2 7/20 0.43
▸ SMN1; SMN2 Q16637 7/20 0.43
▸ MAPT P10636 6/20 0.43
▸ TP53 P04637 5/20 0.43
▸ GAA P10253 3/20 0.43
▸ NFKB1 P19838 2/20 0.43
▸ NFKB2 Q00653 2/20 0.43
▸ RELA Q04206 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ STAT1 P42224 1/20 0.43
▸ GFER P55789 1/20 0.43
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ ATM Q13315 1/20 0.42
▸ HSD17B10 Q99714 5/20 0.40
▸ HCRTR1 O43613 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15290427 0.99 NPC1 (0.44) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL9603921 0.92 NPC1 (0.46) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL8514091 0.92 NPC1 (0.46) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL9603920 0.91 NPC1 (0.40) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL9603925 0.90 NPC1 (0.44) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL9603932 0.90 NPC1 (0.42) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL9603933 0.89 NPC1 (0.45) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL9603922 0.87 NPC1 (0.45) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL9603917 0.86 KDM4E (0.46) NPC1RAB9AALDH1A1HPGDKDM4E
SCHEMBL9603927 0.85 NPC1 (0.45) NPC1RAB9AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device XDH, AOX1, CYP4X1 NPC1 4611/4885RAB9A 3002/4885ALDH1A1 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.