Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9604128 | 1.00 | THRB (0.32) | THRBLMNAGRIK1GRIK2 | |
| SCHEMBL9604117 | 1.00 | THRB (0.32) | THRBLMNAGRIK1GRIK2 | |
| SCHEMBL9604134 | 1.00 | THRB (0.32) | THRBLMNAGRIK1GRIK2 | |
| SCHEMBL9604120 | 1.00 | THRB (0.32) | THRBLMNAGRIK1GRIK2 | |
| SCHEMBL13044529 | 0.83 | — | — | |
| SCHEMBL12708843 | 0.82 | THRB (0.31) | THRBLMNA | |
| SCHEMBL9604118 | 0.79 | THRB (0.33) | THRBLMNA | |
| SCHEMBL8041482 | 0.78 | — | — | |
| SCHEMBL12708845 | 0.78 | — | — | |
| SCHEMBL8041379 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157560-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | XL TERRA, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157560-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | XL TERRA, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120136070-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | XL TERRA, INC. (US) | 2012-05-31 | — | — | US | disclosed |
| US-20120136070-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | XL TERRA, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136070-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | KHK, HKDC1, HK2 | THRB 4404/4885LMNA 4298/4885GRIK1 199/4885 |
| US-20120157560-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | KHK, HKDC1, HK2 | THRB 4404/4885LMNA 4298/4885GRIK1 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.