SCHEMBL96043

SCHEMBL96043

CC1=CC(=O)N(c2cccc(N3C(=O)C=C(C)C3=O)c2)C1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 0.52
FAAH O00519 4/20 0.52
HSP90AA1 P07900 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.43
PARP1 P09874 1/20 0.42
PARP15 Q460N3 1/20 0.42
PARP10 Q53GL7 1/20 0.42
ALDH1A1 P00352 2/20 0.39
PKM P14618 1/20 0.39
HTT P42858 1/20 0.39
ATM Q13315 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
XPO1 O14980 1/20 0.37
GAA P10253 1/20 0.37
CASP6 P55212 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21409967 0.93 MGLL (0.66) MGLLFAAHHSP90AA1L3MBTL1ALDH1A1
SCHEMBL9508528 0.89 MGLL (0.58) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL26659447 0.88 MEN1 (0.47) MGLLFAAHHSP90AA1L3MBTL1PARP1
SCHEMBL21756621 0.86 MGLL (0.46) MGLLFAAHHSP90AA1L3MBTL1PARP1
SCHEMBL774452 0.86 MGLL (0.50) MGLLFAAHALDH1A1PKMMEN1
SCHEMBL14579489 0.84 PARP1 (0.51) MGLLHSP90AA1L3MBTL1PARP1PARP15
SCHEMBL9246650 0.84 TYMS (0.57) L3MBTL1PARP1PARP15PARP10ALDH1A1
SCHEMBL28527836 0.84 MGLL (0.45) MGLLHSP90AA1ALDH1A1MEN1KMT2A
SCHEMBL94147 0.83 MGLL (0.46) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL8885075 0.82 HSP90AA1 (0.52) MGLLHSP90AA1L3MBTL1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1197518-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE WITH THE SAME BRIDGESTONE CORPORATION (JP) 2002-04-17 EP claimed
EP-0397343-B1 Blowing Agents SCHERING IND PROD LTD (GB) 1994-06-15 EP claimed
US-5246975-A Peroxide crosslinked polyethylene foams SCHERING INDUSTRIAL PRODUCTS LIMITED (GB) 1993-09-21 US claimed
EP-0165812-B1 THERMOSETTING IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1988-11-09 EP claimed
EP-0131027-B1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1986-12-17 EP claimed
US-20220106463-A1 RUBBER COMPOSITION, RUBBER MATERIAL, USE OF SAME, AND ADDITIVE OTSUKA CHEMICAL CO., LTD. (JP) 2022-04-07 US disclosed
EP-3233530-B1 TYRE SIDEWALL MICHELIN & CIE (FR) 2020-03-25 EP disclosed
US-RE47886-E1 Tire with improved grip on wet ground COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-03-03 US disclosed
EP-2432826-B1 RUBBER COMPOSITION FOR TIRE COMPRISING AN ACETYLACETONATE COMPOUND MICHELIN & CIE (FR) 2019-09-25 EP disclosed
EP-2877529-B1 TYRE WITH IMPROVED GRIP ON WET GROUND MICHELIN & CIE (FR) 2019-09-11 EP disclosed
US-10035904-B2 Bicycle tire COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-07-31 US disclosed
EP-3083273-B1 TIRE FOR BICYCLE MICHELIN & CIE (FR) 2018-07-11 EP disclosed
US-4161580-A Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US disclosed
US-4089845-A Thermosetting mixtures which are stable on storage from polyimide and .beta. CIBA-GEIGY CORPORATION (US) 1978-05-16 US disclosed
US-4076697-A FROM POLYIMIDES AND POLYCARBOXYLIC ACIDS IN THE PRESENCE OF AN AMINE CIBA-GEIGY CORPORATION (US) 1978-02-28 US disclosed
US-4066621-A CURABLE MIXTURES BASED ON POLYIMIDES OF UNSATURATED DICARBOXYLIC ACIDS AND INDOLE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-4065433-A Process for the manufacture of polyaddition products containing imide groups CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-3950279-A DI- OR TRI-MALEIMIDE, AZOMETHINE, SOLID FOAMING AGENT CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed
US-3947385-A Mixtures containing prepolymers, which can be converted to heat-resistant foamed plastics CIBA-GEIGY CORPORATION (US) 1976-03-30 US disclosed