SCHEMBL9508528

SCHEMBL9508528

CC1=CC(=O)N(c2cccc(Cl)c2)C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.58
KMT2A Q03164 5/20 0.50
ALDH1A1 P00352 5/20 0.50
MAPT P10636 5/20 0.50
MEN1 O00255 4/20 0.50
MAPK1 P28482 2/20 0.50
GAA P10253 3/20 0.46
PGR P06401 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 2/20 0.45
TSHR P16473 2/20 0.44
HTT P42858 1/20 0.44
BCL2A1 Q16548 1/20 0.44
CASP6 P55212 1/20 0.44
HSP90AA1 P07900 1/20 0.43
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
FAAH O00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96043 0.89 MGLL (0.52) MGLLKMT2AALDH1A1MAPTMEN1
SCHEMBL21409967 0.83 MGLL (0.66) MGLLALDH1A1HTTHSP90AA1PKM
SCHEMBL8885538 0.82 TSHR (0.39) MGLLKMT2AALDH1A1MEN1TSHR
SCHEMBL17338891 0.82 TSHR (0.43) KMT2AALDH1A1MEN1SMN1; SMN2TSHR
SCHEMBL26659447 0.81 MEN1 (0.47) MGLLKMT2AALDH1A1MAPTMEN1
SCHEMBL10704906 0.80 MEN1 (0.56) MGLLKMT2AALDH1A1MAPTMEN1
SCHEMBL21756621 0.80 MGLL (0.46) MGLLKMT2AALDH1A1MAPTMEN1
SCHEMBL774452 0.80 MGLL (0.50) MGLLKMT2AALDH1A1MEN1GAA
SCHEMBL10834455 0.79 MGLL (0.58) MGLLKMT2AALDH1A1MAPTMEN1
SCHEMBL9506407 0.79 MEN1 (0.56) MGLLKMT2AALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0267574-B1 HEAT RESISTANT COPOLYMER COMPOSITION Sumitomo Dow Limited (JP) 1993-09-01 EP disclosed
US-4877833-A BLEND OF POLYMERS OF SPECIFIC COMPOSITION SUMITOMO NAUGATUCK CO., LTD. (JP) 1989-10-31 US disclosed