⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6766127 | 0.88 | FFAR1 (0.56) | — | |
| SCHEMBL2392317 | 0.85 | ALDH1A1 (0.44) | — | |
| SCHEMBL95988 | 0.78 | ALDH1A1 (0.70) | — | |
| SCHEMBL776647 | 0.75 | ALDH1A1 (1.00) | — | |
| SCHEMBL777671 | 0.75 | ALDH1A1 (0.67) | — | |
| SCHEMBL194865 | 0.74 | FFAR1 (0.65) | — | |
| SCHEMBL95857 | 0.74 | ALDH1A1 (0.64) | — | |
| SCHEMBL12110783 | 0.73 | ALDH1A1 (0.63) | — | |
| SCHEMBL3908119 | 0.72 | ALDH1A1 (0.48) | — | |
| SCHEMBL96807 | 0.72 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695319-B2 | Glucose conjugates of triptolide, analogs and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-06-30 | — | — | US | claimed |
| EP-2758414-B1 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW SILICONES CORP (US) | 2018-11-21 | — | — | EP | claimed |
| US-9480977-B2 | Ruthenium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-11-01 | — | — | US | claimed |
| US-9293711-B2 | Organic semiconductor formulations | POLYERA CORPORATION (US) | 2016-03-22 | — | — | US | claimed |
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | claimed |
| EP-2758414-A2 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | Dow Corning Corporation (US) | 2014-07-30 | — | — | EP | claimed |
| US-20140042369-A1 | Organic Semiconductor Formulations | USINVEST LLC | 2014-02-13 | — | — | US | claimed |
| WO-2013043787-A2 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | claimed |
| EP-1490367-B1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | claimed |
| US-7348339-B2 | 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent | GLAXO GROUP LIMITED (GB) | 2008-03-25 | — | — | US | claimed |
| US-20050197328-A1 | Imidazopyridine derivatives as kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-09-08 | — | — | US | claimed |
| EP-1490367-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-29 | — | — | EP | claimed |
| WO-2003080610-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | claimed |
| CN-108350217-B | Plastics composite and its production method and purposes | ATP艾歇尔和特罗布斯产品开发股份有限公司 | 2019-12-03 | — | — | CN | disclosed |
| EP-2758414-B1 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW SILICONES CORP (US) | 2018-11-21 | — | — | EP | disclosed |
| US-10043978-B2 | Organic semiconductor formulations | FLEXTERRA, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| EP-0119457-B1 | AGENT FOR REGULATING THE GROWTH OF PLANTS | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |
| EP-0052799-B1 | D-HOMO STEROIDS, THEIR UTILIZATION AND PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-01-30 | — | — | EP | disclosed |
| EP-0052799-A1 | D-homo steroids, their utilization and preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-06-02 | — | — | EP | disclosed |