SCHEMBL777671

SCHEMBL777671

c1ccc(SCSc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
MAPK1 P28482 1/20 0.67
FFAR1 O14842 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
MGLL Q99685 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2C9 P11712 1/20 0.43
HIF1A Q16665 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12110783 0.97 ALDH1A1 (0.63) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT
SCHEMBL12110681 0.88 ALDH1A1 (0.60) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT
SCHEMBL11661294 0.83 ALDH1A1 (0.55) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT
SCHEMBL24089845 0.83 ALDH1A1 (0.55) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT
SCHEMBL19514806 0.81 ALDH1A1 (0.52) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT
SCHEMBL776647 0.80 ALDH1A1 (1.00) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT
SCHEMBL10927014 0.79 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTCYP1A2CYP3A4
SCHEMBL7896246 0.79 ALDH1A1 (0.56) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT
SCHEMBL19655459 0.78 ALDH1A1 (0.43) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT
SCHEMBL30255528 0.77 MAOA (0.52) ALDH1A1MAPK1FFAR1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118767996-A Passivation type sulfided hydrogenation catalyst and preparation method and application thereof 国家能源投资集团有限责任公司 2024-10-15 CN claimed
CN-113707933-B Preparation method of solid electrolyte nano dispersion liquid of lithium ion battery and solid electrolyte nano dispersion liquid 浙江蓝珧新材料科技有限公司 2024-04-09 CN claimed
US-20230079918-A1 ELECTROCHEMICAL ELEMENT AND METHOD FOR MANUFACTURING SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2023-03-16 US claimed
EP-4109636-A1 ELECTRODE STRUCTURE, ELECTRODE STRUCTURE FOR POSITIVE ELECTRODE OF METAL-AIR BATTERY COMPRISING SAME, AND METHODS FOR MANUFACTURING SAME Industry-University Cooperation Foundation Hanyang University ERICA Campus (KR) 2022-12-28 EP claimed
US-20220407149-A1 ELECTRODE STRUCTURE, ELECTRODE STRUCTURE FOR POSITIVE ELECTRODE OF METAL-AIR BATTERY COMPRISING SAME, AND METHODS FOR MANUFACTURING SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2022-12-22 US claimed
CN-115136391-A Electrode structure, electrode structure for positive electrode of metal-air battery comprising same, and method for producing same 汉阳大学校ERICA产学协力团 2022-09-30 CN claimed
CN-113707933-A Preparation method of solid electrolyte nano dispersion liquid of lithium ion battery and solid electrolyte nano dispersion liquid 北京卫蓝新能源科技有限公司 2021-11-26 CN claimed
US-20110130482-A1 Process for preparing armatic thiophenyl ketones PRETOR ROGER 2011-06-02 US claimed
US-7622526-B2 Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material ESSILOR INTERNATIONAL (FR) 2009-11-24 US claimed
EP-1670852-B1 THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL ESSILOR INT (FR) 2008-12-10 EP claimed
EP-1799638-B1 PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES CIBA HOLDING INC (CH) 2008-07-30 EP claimed
EP-1799638-A1 PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-06-27 EP claimed
US-20060270771-A1 Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2006-11-30 US claimed
WO-2006034966-A1 PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-06 WO claimed
US-12620652-B2 Electrode structure, electrode structure for positive electrode of metal-air battery comprising same, and methods for manufacturing same FLEXOLYTE (KR) 2026-05-05 US disclosed
US-20250331405-A1 DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2025-10-23 US disclosed
CN-118767996-A Passivation type sulfided hydrogenation catalyst and preparation method and application thereof 国家能源投资集团有限责任公司 2024-10-15 CN disclosed
EP-0088831-A1 Process for the preparation of thioethers GIST-BROCADES N.V. (NL) 1983-09-21 EP disclosed
EP-0021883-A2 N-acyl-amino acid derivatives and pharmaceutical compositions containing them, intermediates and starting compounds MERRELL TORAUDE ET COMPAGNIE (FR) 1981-01-07 EP disclosed
US-4029712-A OXIDATION OF MERCAPTAL SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130482-A1 Process for preparing armatic thiophenyl ketones ACOT7, AGPAT2, COASY ALDH1A1 1816/4885MAPK1 3795/4885FFAR1 1578/4885
US-12620652-B2 Electrode structure, electrode structure for positive electrode of metal-air battery comprising same, and methods for manufacturing same TMCO1, TMEM165, TPO ALDH1A1 4140/4885MAPK1 712/4885FFAR1 4763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.