Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.45 |
| ▸ | DRD3 | P35462 | 9/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7328010 | 0.89 | DRD2 (0.56) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL11181368 | 0.83 | DRD2 (0.65) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL7333690 | 0.81 | DRD2 (0.66) | DRD2DRD3DRD4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7337717 | 0.80 | DRD2 (0.64) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL7332023 | 0.80 | DRD2 (0.41) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL8672825 | 0.79 | HTR1A (0.59) | DRD2DRD3DRD4HTR1ASIGMAR1 | |
| SCHEMBL7334693 | 0.79 | DRD2 (0.71) | DRD2DRD3DRD4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7938715 | 0.78 | HTR1A (0.58) | DRD2DRD3DRD4HTR1ASIGMAR1 | |
| SCHEMBL7020915 | 0.78 | DRD2 (0.59) | DRD2DRD3DRD4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL9596487 | 0.78 | DRD2 (0.69) | DRD2DRD3DRD4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196454-A | METHOD OF TREATING DISORDERS OF THE DOPAMINERGIC SYSTEMS USING 2,5-DIAMINOTETRALINES | BOEHRINGER INGELHEIM KG (DE) | 1993-03-23 | — | — | US | disclosed |