Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2575880 | 0.88 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2575878 | 0.88 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL9606665 | 0.80 | P2RX7 (0.77) | P2RX7 | |
| SCHEMBL2579576 | 0.72 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2579574 | 0.72 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2580789 | 0.70 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2574351 | 0.70 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2580787 | 0.70 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2574353 | 0.70 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2581958 | 0.69 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049478-B1 | SUBSTITUTED N-PHENYLMETHYL -5-OXO-PROLINE-2-AMIDES AS P2X7-RECEPTOR ANTAGONISTS AND THEIR METHODS OF USE | GLAXO GROUP LTD (GB) | 2012-05-30 | — | — | EP | disclosed |