Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607170 | 0.86 | RAB9A (0.51) | SLC6A4EPHX2NR1H4RAB9AALDH1A1 | |
| SCHEMBL13780117 | 0.82 | KAT6A (0.52) | MRGPRX4MAPK14KAT6A | |
| SCHEMBL8580572 | 0.81 | PRSS1 (0.46) | MRGPRX4RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9607399 | 0.79 | BCL2L1 (0.41) | MRGPRX4NLRP3SLC6A4EPHX2NR1H4 | |
| SCHEMBL6141283 | 0.78 | HDAC3 (0.54) | TRPV1EPHX2NR1H4RAB9AMAPT | |
| SCHEMBL8515213 | 0.76 | SLC6A4 (0.47) | MRGPRX4HTR2CTRPV1SLC6A4ALDH1A1 | |
| SCHEMBL365751 | 0.75 | SMN1; SMN2 (0.49) | MAPTSMN1; SMN2MAPK14 | |
| SCHEMBL3033628 | 0.75 | BCL2 (0.50) | MRGPRX4RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9607172 | 0.74 | EPHX2 (0.52) | TRPV1SLC6A4EPHX2NR1H4RAB9A | |
| SCHEMBL365586 | 0.74 | MAPK14 (0.55) | MRGPRX4SMN1; SMN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |