Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175829 | 0.86 | PDE2A (0.43) | EPHX2PDE2AMAOBPOLB | |
| SCHEMBL9607170 | 0.80 | RAB9A (0.51) | SLC6A4EPHX2NR1H4HRH3PPARA | |
| SCHEMBL9607053 | 0.79 | MRGPRX4 (0.55) | SLC6A4EPHX2NR1H4MRGPRX4NLRP3 | |
| SCHEMBL12780426 | 0.77 | FFAR4 (0.44) | EPHX2PDE2APOLB | |
| SCHEMBL8514972 | 0.75 | SLC6A4 (0.46) | SLC6A4PDE2ATSHRDAO | |
| SCHEMBL27837804 | 0.75 | HSP90AB1 (0.60) | POLBTSHR | |
| SCHEMBL9607440 | 0.74 | DAO (0.40) | MRGPRX4DAO | |
| SCHEMBL9607438 | 0.74 | PDE2A (0.52) | BCL2L1SLC6A4EPHX2PDE2AEPHX1 | |
| SCHEMBL27719541 | 0.73 | THRB (0.45) | EPHX2POLBMRGPRX4 | |
| SCHEMBL9607166 | 0.73 | DAO (0.42) | SLC6A4POLBTSHRDAONLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |