Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607506 | 1.00 | EPHX2 (0.45) | EPHX2PPARGPPARAPOLBCTNNB1 | |
| SCHEMBL8515651 | 0.87 | KMT2A (0.48) | EPHX2CTNNB1TCF7L2SMN1; SMN2CYP1A2 | |
| SCHEMBL9607492 | 0.86 | POLB (0.43) | EPHX2PPARGPPARAPOLBSMN1; SMN2 | |
| SCHEMBL8535567 | 0.86 | SMN1; SMN2 (0.49) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8535569 | 0.86 | SMN1; SMN2 (0.49) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9607414 | 0.85 | TRPV1 (0.47) | EPHX2PPARGPPARAPOLBSMN1; SMN2 | |
| SCHEMBL9607177 | 0.83 | KMT2A (0.50) | EPHX2POLBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9607090 | 0.83 | PDE2A (0.42) | EPHX2PPARGPPARAPOLBSMN1; SMN2 | |
| SCHEMBL9607491 | 0.82 | HTR1D (0.43) | EPHX2SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL3858960 | 0.80 | GAA (0.51) | SMN1; SMN2ALDH1A1MAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |