Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607492 | 0.91 | POLB (0.43) | PPARAPPARGABL1EPHX2MEN1 | |
| SCHEMBL9607414 | 0.84 | TRPV1 (0.47) | PPARAPPARGABL1EPHX2MEN1 | |
| SCHEMBL9607506 | 0.83 | EPHX2 (0.45) | PPARAPPARGEPHX2MAPTPOLB | |
| SCHEMBL9607091 | 0.83 | EPHX2 (0.45) | PPARAPPARGEPHX2MAPTPOLB | |
| SCHEMBL8515707 | 0.78 | KMT2A (0.44) | PPARAABL1EPHX2MEN1KMT2A | |
| SCHEMBL9607177 | 0.77 | KMT2A (0.50) | ABL1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9607491 | 0.76 | HTR1D (0.43) | EPHX2MEN1KMT2AMAPTKCNH2 | |
| SCHEMBL28551944 | 0.72 | MAPT (0.55) | MEN1GAAKMT2AMAPTPOLB | |
| SCHEMBL8535567 | 0.71 | SMN1; SMN2 (0.49) | MEN1GAAKMT2AMAPTPOLB | |
| SCHEMBL8535569 | 0.71 | SMN1; SMN2 (0.49) | MEN1GAAKMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |