Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607492 | 0.88 | POLB (0.43) | TRPV1MAPK1MAPTPOLBEPHX2 | |
| SCHEMBL9607506 | 0.85 | EPHX2 (0.45) | TRPV1MAPTPOLBEPHX2PPARG | |
| SCHEMBL9607091 | 0.85 | EPHX2 (0.45) | TRPV1MAPTPOLBEPHX2PPARG | |
| SCHEMBL9607090 | 0.84 | PDE2A (0.42) | MAPTNPSR1POLBEPHX2PPARG | |
| SCHEMBL9607177 | 0.79 | KMT2A (0.50) | MAPTPOLBEPHX2KMT2AMEN1 | |
| SCHEMBL9607491 | 0.79 | HTR1D (0.43) | MAPK1MAPTEPHX2KMT2AMEN1 | |
| SCHEMBL8515707 | 0.74 | KMT2A (0.44) | TRPV1EPHX2PPARAKMT2AMEN1 | |
| SCHEMBL8515651 | 0.72 | KMT2A (0.48) | TRPV1MAPTEPHX2KMT2ASMN1; SMN2 | |
| SCHEMBL8515949 | 0.71 | POLB (0.56) | MAPTPOLBEPHX2PPARGPPARA | |
| SCHEMBL8535569 | 0.71 | SMN1; SMN2 (0.49) | MAPTNPSR1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |